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AP Biology DNA Structure & Replication. Nucleic Acid Structure.

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Presentation on theme: "AP Biology DNA Structure & Replication. Nucleic Acid Structure."— Presentation transcript:

1 AP Biology DNA Structure & Replication

2 Nucleic Acid Structure

3 Complimentary Base Pairing

4 S Phase of Cell Cycle

5 Theta Replication in Prokaryotes Origin of replication Replication fork Termination of replication

6 Linear Replication in Eukaryotes

7 . The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C.

8 . The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C. The first step in replication is separation of the two DNA strands.

9 Semi Conservative process of DNA Replication The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C. The first step in replication is separation of the two DNA strands. Each parental strand now serves as a template that determines the order of nucleotides along a new, complementary strand.

10 Origins and Replication bubbles

11 DNA Replication

12 DNA Replication by adding Nucleosides on the 3’ end New strand 5 end Phosphate Base Sugar Template strand 3 end 5 end 3 end 5 end 3 end 5 end 3 end Nucleoside triphosphate DNA polymerase Pyrophosphate

13 5 Carbon Sugar Important Parts (It could be DNA or RNA)

14 Helicase is the GREEN “blob”

15 RNA Primer (Remember, RNA is temporary)

16 . New strand 5 end Phosphate Base Sugar Template strand 3 end 5 end 3 end 5 end 3 end 5 end 3 end Nucleoside triphosphate DNA polymerase Pyrophosphate

17 Nucleotide Excision Repair

18 Telomere Removal at the Chromosome Ends End of parental DNA strands 5 3 Lagging strand 5 3 Last fragment RNA primer Leading strand Lagging strand Previous fragment Primer removed but cannot be replaced with DNA because no 3 end available for DNA polymerase 5 3 Removal of primers and replacement with DNA where a 3 end is available Second round of replication 5 3 5 3 Further rounds of replication New leading strand Shorter and shorter daughter molecules

19 Apoptosis in the hand


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