1. Information Representation Working Group: Kickoff ‘08 IRWG Working Group May 13, 2008

2. Agenda Elaine Freund Introductions to team Establish meeting schedule How meetings work Subha Madhavan Introduction to Information Representation Baris Suzek Kick-off Background Suggested tasks 2008 Charter Homework

3. Introductions 2008 IRWG Members Introductions: - Name & Institution - Background - caBIG activities Elaine Freund efreund@3rdmill.com Li Kramer kramer_li@bah.com Subha Madhavanmadhavas@mail.nih.gov Juli Klemm klemmj@mail.nih.gov Baris E. Suzek bes23@georgetown.edu Bob FreimuthFreimuth.Robert@mayo.edu Ted Liefeld liefeld@broad.mit.edu Sue Panpansu@mail.nih.gov Mukesh SharmaSharmam@pathology.wustl.edu Grace Staffordgrace.stafford@jax.org Lalitha Viswanathviswanathl@mail.nih.gov

4. Meeting Schedule Working Group Meetings 2 meetings per month Notes posted in GForge Link sent on listserv Include attendance and activities in Status Reports Participant Status Report 1 Jul 28, 2008 Participant Status Report 2 Oct 27, 2008 Participant Status Report 3 Feb 1, 2009 Activities Charter (and reassessment week of Sept 29) 3 deliverables Task Group Artifact #1July 28, 2008 Task Group Artifact #2Oct 27, 2008 Task Group Artifact #3Feb 6, 2009 Suggested Date/Times?

5. Getting Underway Remarks from Subha Madhavan – NCI Representative Baris Suzek – Kick off

6. IRWG Goal The Information Representation Working Group has been established to guide interoperability analysis and develop a tactical approach for harmonizing ICR informatics systems that support and manage molecular information and analysis. This may entail working in a matrixed group, with members from other ICR Task Groups, other domains or cross-cutting workspaces.

7. IRWG Objectives Work plan including how to work with VCDE and appropriate teams with which to iterate work products. Report on review of ICR tools (usage, maturity) and select those to further evaluate when creating a domain model Analysis of VCDE “backbone” model and CDE usage reports for utility in creating an ICR DAM Create a draft domain model with definition of CDEs for the ICR domain White paper on harmonization strategy Resolve issues of data representation and description including binary mark-up and endpoint reference metadata and sequencing. Identify caBIG vocabulary and/or CDE standard candidates within ICR WS and bring them to VCDE WS's attention Recommend new service-level metadata items (published workflows, input boundaries, backend computational support). Engage in Dynamic extensions uses and development

8. IRWG Charter Suggestions Related to ICR DAM / draft domain model development: Review ICR tools (usage, maturity) and select those to further evaluate when creating a domain model Analyze the VCDE “backbone” model and CDE usage reports for utility In creating an ICR DAM Create a draft domain model with definition of CDEs for the ICR domain Identify caBIG vocabulary and/or CDE standard candidates within ICR WS and bring them to VCDE WS's attention White paper on harmonization strategy Work plan including how to work with VCDE and appropriate teams with which to iterate work products

9. IRWG Charter Suggestions Others: Resolve issues of data representation and description including Binary mark-up Endpoint reference metadata Recommend new service-level metadata items such as Published workflows Input boundaries Backend computational support Engage in Dynamic extensions uses and development Work plan including how to work with VCDE and appropriate teams with which to iterate work products.

10. Related Material Binary Data Formats White Paper https://gforge.nci.nih.gov/docman/view.php/455/10991/BDF-Whitepaper-Final.doc High-throughput Data WG Final Report - End-point references section http://ccis1716.duhs.duke.edu/wiki/index.php?title=HTP:EndpointReferences Workflow WG Next Steps https://gforge.nci.nih.gov/docman/view.php/332/11258/workflow_next_steps_vcde_f eedback.dochttps://gforge.nci.nih.gov/docman/view.php/332/11258/workflow_next_steps_vcde_f eedback.doc BRIDG Model http://www.bridgmodel.org/ High-impact CDEs work by VCDE CDE leadership group https://gforge.nci.nih.gov/docman/view.php/357/10348/20080130_Arch_VCDE_F2F _Day3_High_Impact_CDE_Identification.ppthttps://gforge.nci.nih.gov/docman/view.php/357/10348/20080130_Arch_VCDE_F2F _Day3_High_Impact_CDE_Identification.ppt

11. Related Material Backbone Model Gforge site http://gforge.nci.nih.gov/projects/model-harmony List Server https://list.nih.gov/archives/cabig_lrg_mod_harm-l.html Final Report http://gforge.nci.nih.gov/frs/download.php/1119/caBIG_Model_Harmonizat ion_whitepaper.dochttp://gforge.nci.nih.gov/frs/download.php/1119/caBIG_Model_Harmonizat ion_whitepaper.doc Backbone Model http://gforge.nci.nih.gov/frs/download.php/792/ICR_and_TBPT_Model_Ha rmonization_Final.EAPhttp://gforge.nci.nih.gov/frs/download.php/792/ICR_and_TBPT_Model_Ha rmonization_Final.EAP

12. Next Steps Draft charter document Group communications: Discussion list gForge site for IRWG Agenda for next meeting Finalizing charter Finalizing deliverables Identification of next steps based on charter