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Presented by Nai-Hsin Chi National Taiwan University Hospital

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1 Presented by Nai-Hsin Chi National Taiwan University Hospital
ECMO extracorporeal membrane oxygenation extracorporal life support /9/22 Presented by Nai-Hsin Chi National Taiwan University Hospital

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3 ECMO  prolonged partial cardiopulmonary bypass

4 ECMO vs CPB reservoir

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8 CPB vs ECMO Yes Yes in high flow

9 composite of ECMO Blood pump centrifugal pump membrane oxygenator
roller pump+ control-bladder membrane oxygenator hollow fiber oxygenator silicone membrane oxygenator Heater

10 ECMO 機器

11 ECMO主機

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13 Centrifugal pump

14 滾輪式幫浦加囊狀控制裝置

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16 Pig-Tail 排氣用 接氧氣

17 Cannula

18 Arterial cannula

19 MX-2 monitor

20 氣體流量表

21 ECMO Short-term cardiopulmonary support 1-2 weeks
Bridge to decision Buy time to decide the next step Recovery Transplantation long-term device (ventricular assist device) Operation (CABG, pulmonary embolectomy,..) Give-up

22 for lung 1. support : O2 supply & CO2 removal
2. rest : reduce ventilator induced lung injury

23 for heart support : improve systemic perfusion rest :
↓catecholamine ↓myocardial work decrease preload requirement and congestion

24 ECMO Type VV - ECMO VA - ECMO

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26 VV-ECMO indication : for lung disease only
purpose : to decrease barotrauma ventilator setting : PC mode, PEEP >10 , PIP < 35 , VR --> PaCO2, FiO2--> PaO2

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28 VA-ECMO advantage : 1. both lung & heart support

29 Application of ECMO As a mechanical circulatory support:
Post-cardiotomy cardiogenic shock Double bridge (ECMO VAD HTx) Acute myocarditis AMI cardiogenic shock (ECPR) Rescue for acute pulmonary embolism Ventilatory support ARDS Neonatal pulmonary diseases

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34 Different patients Different situation  Different treatment t

35 ECMO in NTUH 1994 Aug. 11  2003 Dec. 31

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41 ECMO工作車 All you need to set up ECMO Put everything on the wheel Then,
OR, ICU, cath room, ES, ward, etc

42 Bleeding Anticoagulation Thrombus

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45 尿紅

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49 Five-Year Results of 219 Consecutive Patients Treated With Extracorporeal Membrane Oxygenation for Refractory Postoperative Cardiogenic Shock Ann Thorac Surg 2004; 77:151-7

50 Results Mortality Cause : 86 (39%) did not improved and weaning
133 (61%) successfully weaned from ECMO Mortality Cause : Refractory myocardial failure : 118(71%) MoF : 24(14%) Cerebral infarction/bleeding : 8(5%) Sepsis : 6(4%) ARDS: 4(2.5%) DIC : 2(1%) Bowel ischemia : 2(1%) Pulmonary embolism: 2(1%) ET tube into esophagus : 1(0.5%) 52 (39%) discharge Mean hospital stay: 29.924 days

51 Bridge VAD : 8 Transplant : 4 survival HeartMart : 2
Heart Transplant : Survival Berlin Heart : 6 (Biventricular : 4, Univentricular : 2) Successfully weaning : 1 Die : 5

52 ECMO Short-term cardiopulmonary support 1-2 weeks
Bridge to decision Buy time to decide the next step Recovery Transplantation long-term device (ventricular assist device) Operation (CABG, pulmonary embolectomy,..) Give-up

53 ECMO Advantage: Both children & adult (wide range of BW)
Flexible cannulation site: femoral, neck, chest Higher support Rapid & easy set-up & remoral Disadvantage: Bleeding Bedridden Infection SIRS Labor-intensive Partial CP support

54 Thank you


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