1. Next Generation Locator R-TX ™ Attachment Solution GMT 45612. Locator ® and Locator R-Tx TM is a registered trademark of Zest Anchors Inc. Distributed by Nobel Biocare Inc © Nobel Biocare Services AG, 2016. All rights reserved. Nobel Biocare, the Nobel Biocare logotype and all other trademarks are, if nothing else is stated or is evident from the context in a certain case, trademarks of Nobel Biocare. Please refer to nobelbiocare.com/trademarks for more information. Product images are not necessarily to scale. Disclaimer: Some products may not be regulatory cleared/released for sale in all markets. Please contact the local Nobel Biocare sales office for current product assortment and availability. For prescription use only. Caution: Federal (United States) law restricts this device to sale by or on the order of a licensed dentist. See Instructions for Use for full prescribing information, including indications, contraindications, warnings and precautions. For prescription use only. Caution: Federal (United States) law restricts this device to sale by or on the order of a licensed dentist. See Instructions for Use for full prescribing information, including indications, contraindications, warnings and precautions.

2. Patients wearing conventional dentures may be suffering of daily complications and benefit from implant-retained overdentures 2 Frequent dentist visits for denture adjustments to relieve sore spots Always worrying that their dentures falls out while talking Constant denture movement affecting their speech Adhesives that ruin their taste of food It is painful to eat Progressive jaw bone resorption

3. There are different advantages of implant restorations for the edentulous patients:  Improved function, stability and retention  Maintain hard tissues 1  Avoid use of denture adhesives Overall aim  Increase patients confidence and quality of life Implant treatment offers a solution for edentulous patients 1: H. Frost (1994) Wolff’s Law and bone’s structural adaptation to mechanical usage: an overview for clinicians, The Angle Orthodontist, 64, 3, 175-188

4. But there is more than one way to treat edentulous patients with implants 4 Bone resorption patterns Soft tissue loss Patient hygiene Patient budget Patient medical history Bridge + Zygoma implants Bridge + 5-6 implants All-on-4 Bar + implants Overdenture + Locators Locator ® is a registered trademark of Zest IP Holdings, LLC

5. Missing teeth only Mild resorption Moderate resorption Severe resorption Front view Side view Locator R-TX ™ is particularly indicated for certain resorption patterns and indications Area of application Locator R-Tx TM is a registered trademark of Zest IP Holdings, LLC

6. Easy denture seating with pivoting technology Duratec ® coating designed to increase strength, wear resistance and reduction in roughness “Self-locating” engagement Narrow coronal geometry allows the patient to easily align and properly seat the overdenture. Practical denture attachment housing design. Horizontal grooves and flats resist vertical and rotational movement The design resists edge deformation. The system utilizes only one set of retention inserts with straightforward retention values Convenient All-in-One packaging: 4 x nylon retention inserts 1 x attachment housing 1 x black processing insert 1 x block-out spacer Available for Nobel Biocare Conical Connection, Tri- channel and External Hexagon connections

7. 7 Aesthetic and wear resistant coating Dual retentive surfaces for engagement, plus narrower coronal geometry for easy seating of the overdenture. Convenient all-in-one packaging.050"/1.25mm hex-drive mechanism Tolerance for a 60°between diverging implants Enhanced geometry to resist movement and anodized pink improves esthetics Locator R-Tx TM is a registered trademark of Zest IP Holdings, LLC

8. Locator R-TX ™ Dimensional Comparison 8.050“ /1.25mm hex-drive mechanism simplifies placement Small center cavity limits the area for food and plaque accumulation The metal slot feature allows the clinician to disengage a retention insert without the risk of tearing their gloves Dual-sided tool for easy insertion and removal of the Locator R-Tx retention insert.

9. You’re a dental technician - what’s next Discover…  Benefit from the introduction offer that includes tools for free and allows your customers to benefit from similar offer conditions Launch…  With the support of Nobel Biocare introduce the new Locator R-Tx to your customers. With a hands-on activity, get your customers proficient in using Locators and develop with them a show model to demonstrate the system to their patients.  See the Study Club presentation template 9

10. You’re a clinician - what’s next Discover…  Try the Locator R-TX with the offer including tools for free  Step-by-step guide how to use Locator R-Tx  Prepare a show model with your dental lab: cast with Locator analogs and a denture with Locator housing Launch…  Use your show model to take your patients through the advantages of implant assisted dentures. 10 Locator ® R-Tx TM is a registered trademark of Zest IP Holdings, LLC

11. Thank you

12. Locator R-Tx™ - Attachment System Conical Connection1.0mm2.0mm3.0mm4.0mm5.0mm6.0mm Narrow Platform (NP)REF30506-01REF30506-02REF30506-03REF30506-04REF30506-05REF30506-06 Regular Platform (RP)REF30507-01REF30507-02REF30507-03REF30507-04REF30507-05REF30507-06 Wide Platform (WP)REF30508-01REF30508-02REF30508-03REF30508-04REF30508-05 Tri-Channel Connection0.0mm1.0mm2.0mm3.0mm4.0mm5.0mm6.0mm Narrow Platform (NP)REF30500-00REF30500-01REF30500-02REF30500-03REF30500-04REF30500-05REF30500-06 Regular Platform (RP)REF30501-00REF30501-01REF30501-02REF30501-03REF30501-04REF30501-05REF30501-06 Wide Platform (WP)REF30502-01REF30502-02REF30502-03REF30502-04REF30502-05 External Hex Connection1.0mm2.0mm3.0mm4.0mm5.0mm6.0mm Narrow Platform (NP)REF30510-01REF30510-02REF30510-03REF30510-04REF30510-05 Regular Platform (RP)REF30511-01REF30511-02REF30511-03REF30511-04REF30511-05REF30511-06 Wide Platform (WP)REF30512-01REF30512-02REF30512-03REF30512-04REF30512-05 addition not available for launch

13. Locator R-Tx™ - Processing Components & Tooling Retention Replacement Males Zero Retention Insert (4/pkg)REF30001-01 Low Retention Insert (4/pkg) REF30002-01 Medium Retention Insert (4/pkg)REF30003-01 High Retention Insert (4/pkg)REF30004-01 Extra High Retention Insert (4/pkg)*REF30005-01 Processing Components Processing Insert (4/pkg)REF30012-01 Denture Attachment Processing Assembly (4/pkg) REF30013-01 Abutment Analog 3.35mm (4/pkg)REF30014-01 Abutment Analog 4.0mm (4/pkg) REF30015-01 Abutment Analog 5.0mm (4/pkg)REF30016-01 Impression Coping (4/pkg)REF30017-01 Processing Spacer (4/pkg)REF30018-01 White Block Out Spacer (20/pkg)REF08514 Tools 050” (1.25mm) Hex Latch Driver for Torque Wrench or Handpiece REF08008 Retention Insert Tool REF30021-01 * Not included in "All-in-One“ packaging.