1. Aiym Kaiyrlykyzy 1, MD, Sharon Welburn 1, BS, Igor Linkov 2, PhD, Kyle Freese 3, MPH, Dana Bovbjerg 4, PhD, Faina Linkov 3, MPH, PhD University of Pittsburgh, Department of Epidemiology 1, Consultant 2, Magee-Womens Research Institute, Department of Ob/Gyn 3, University of Pittsburgh School of Medicine, Department of Psychiatry 4 Introduction Method Discussion Results We worked with a diverse group of endometrial cancer/weight loss stakeholders to collect information about factors involved in the decision- making process that aids in patient centered obesity care. Stakeholders 3 gynecologic oncology providers, 2 bariatric surgery providers, 4 researchers, 5 endometrial cancer patients and caregivers N = 13 One stakeholder was not present to complete the survey. Measure A laboratory-developed, self-report 4 question survey–2 questions had 9 choices, 1 question with 3 choices, and an open-ended question–that focused on factors important in making decisions about enrolling in weight loss/lifestyle intervention programs. Data Analysis Descriptive statistics were used to determine which factors were important in the decision-making process for lifestyle changes This work was supported by Magee-Womens Research Institute & Foundation. Correspondence should be directed to Aiym Kaiyrlykyzy, Sharon Welburn, or Dr. Linkov at the MWRI, 3380 Boulevard of the Allies, Suite #334, Pittsburgh, PA 15213, or by email at aik11@pitt.edu, scw42@pitt.edu, or faina.linkov@gmail.com. Important factors identified through this research were consistent with what has been described in the literature. During the stakeholder meeting, providers and endometrial cancer patients alike were interested in future collaboration through research process and implementation. In the future, these findings can be used to develop a patient centered decision support framework that will aid obese endometrial cancer survivors in choosing a weight loss intervention to help avoid future obesity-related complications. This decision support tool will increase the likelihood of patient adherence to treatment, as it will empower endometrial cancer patients to select treatments most consistent with their values and needs. Endometrial cancer is the most common gynecologic malignancy in the U.S. Nearly two thirds of endometrial cancer survivors are overweight or obese, and most do not adopt healthier lifestyle after diagnosis. Traditional clinical research is shifting towards improving patient centered outcomes research (PCOR) strategies - helping patients make better informed health care decisions. PCOR potentially improves health care delivery and outcomes research by involving the voices of stakeholders. Learning more about decision-making process of obese endometrial cancer patients when considering weight loss interventions is important in reducing risk of recurrent cancer and other chronic diseases associated with malignancies. Our objective was to identify important factors in the decision making process about lifestyle interventions for endometrial cancer survivors. % of Stakeholders rating each factor as important Intervention Associated Factors The data collected will be used to implement an individualized tool to help patients determine which intervention is best for them. The tool will allow patients to choose between 5 alternatives presented (healthy eating, lifestyle intervention, bariatric surgery, online educational program, or no treatment). Availability on mobile device Effort Knowledge about existing interventions Ability to do with family Finances/Cost of weight loss programs Time Availability Convenience Family Support Understanding the need to lose weight Personal Factors: Convenience (69.23%), effort (61.54%), and finances (61.54%) were ranked as most important personal factors. Intervention Associated Factors: Overall effectiveness (76.92%), ease of access (69.23%), and reduction of disease (69.23%) were ranked most important intervention-associated factors. Healthcare Provider Factors: Provider knowledge (76.92%) about available options was ranked as the most important provider factor followed by provider support (62.54%) and availability (53.85%) of lifestyle change program at the provider’s office were ranked as the most important healthcare provider factors. % of Stakeholders rating each factor as important Personal Factors that Affect Lifestyle Change Ease of access to facilities Pain Reduction of disease Interest in behavioral interventions Parking availability Side effects Overall effectiveness in weight loss Perception of effectivenessSurgical consideration Healthcare Provider Factors Availability of lifestyle change program at provider’s office Knowledge of the healthcare provider about available options Provider supportive of lifestyle change % of Stakeholders rating each factor as important Factors Figure 3. Frequency of healthcare provider factors Figure 2. Frequency of intervention associated factors Figure 1. Frequency of personal factors that affect lifestyle change decision Factors Stakeholder group meeting picture. May 16, 2013 Figure 4. Decision support tree using DECERNS Software. More information can be found at http://www.decerns.comhttp://www.decerns.com