1. Introduction Intravenous urography (IVU) has long been the major and first-line modality in evaluating GU tract abnormalities. The imaging findings are prone to be affected by artifacts (bowel gas or bowel content), and poor or non-opacified urinary tract (due to impairment renal function). For radiolucent stones, IVU is also limited. Computed tomography urography (CTU) has become the modality of choice in imaging the urinary tract. With few exceptions, most notably that of the unenhanced CT performed for acute flank pain and stone disease, many urological symptoms and conditions are now investigated with CTU. Continuing improvements in the spatial resolution and speed of newer CT scanners, combined with advanced multiplanar and volume-rendered image reconstruction, have made CTU a comprehensive examination whereby the kidneys and upper collecting system, ureters, and urinary bladder can be evaluated in one setting. Materials and Methods From May 2012 to September 2014, 324 consecutive patients (212men and 112 women, age ranged from 15 to 83 years old, mean age 55.6 years) who had acute renal colic or hematuria that highly suggested urinary tract abnormalities underwent non-enhanced helical and excretory phase CT for evaluating the urinary system. The non-enhanced and excretory phase, contrast-enhanced helical CT studies were performed with a 64 slice MDCT scanner (Brilliance PHILIPS). Three-dimensional (3D) reconstructions of the nonenhanced and excretory phase, contrast-enhanced helical CT scans were performed at a workstation (BARCO). Noncontrast images extend from the top of the kidneys through the bladder. Intravenous contrast is following a 90- to 100-sec delay, scanning of the abdomen and pelvis performed during the nephrographic-phase. The final acquisition is during the excretory-phase after a 12- to 15-min delay. Department of Radiology, Ditmanson Medical Foundation Chia-Yi Christian Hospital Guo Chiang-Yang Results Noncontrast images are obtained to evaluate for calculi, fat-containing lesions and parenchymal calcifications. Nephrographic-phase optimizes small renal mass detec- tion. Excretory-phase is opacification and distention of the collecting systems, ureters, and bladder. Of these 324 patients, 108 cases were proved to have urolithiasis, 63 cases were with renal or uretera tumors. and there were 153 cases of other urinary system disorders. Conclusion In conclusion, CT urography is a newly developed modal- ity for evaluating urinary tract abnormalities. Our prelimin- ary results show CT urography is exceptional in diagnos- ing urinary tract abnormalities, specially in urolithiasis. It also can provide more information on the non-urinary tra- ct abnormality of the patients. The American Urological Association Best Practices Policy guidelines recommend IV or CT urography as the initial imaging test for patients with asymptomatic microscopic hematuria. The American College of Radiology rated CTU as the most appropriate imaging procedure in the evaluation of hematuria. Keywords : CT urography, hematuria, urolithiasis A 2 cm enhancing lesion is seen in left middle third ureter with hydronephrosis. TCC should be suspected. Wall thickening of urinary bladder with soft tissue mass at left lateral wall. DDx: urinary bladder CA.