1. PERIPHERAL VASCULAR DISEASES DR. Mohamed Seyam PhD. PT. Assistant Professor Of Physical Therapy For Cardiovascular /Respiratory Disorder

2. Objectives Understand/describe the normal structure and function of the lymphatic system. Identify risk factors affecting the normal drainage of the lymphatic system. Discuss diseases or procedures that could predispose a patient to lymphedema. Explain assessment of a patient with lymphedema Discuss management of lymphedema.

3. Lymphatic system( tissues and vessels) The lymphatic system filters and collects lymph and large molecules in the interstitial space that come from the intravascular space. Main functions: Helps balance the body’s fluid and Protects the body from infection Normally, the heart pumps so strongly that it causes 20-30 liters of plasma per day to leak from the capillaries. This is the interstitial fluid, which the lymphatic system drains, filters, and returns to the heart. Lymphatic vessels are similar to veins, but with thinner walls to allow larger proteins to permeate through. unidirectional flow and no circulation.

4. Lymph nodes 1.S upraclavicular 2.Retroperitoneal 3.Trachea 4. Thoracic 5.Abdominal 6.Axilla 7.The pelvic area 8.Inguinal 9.Tonsils 10. spleen 11.Intestinal wall 12.bone marrow.

5. Lymph nodes filter harmful substances and contain lymphocytes that activate the immune system. The lymph system carries the lymphocytes throughout the body to respond to antigens and communicate responses to other parts of the body. Lymph then travels through multiple lymphatic channels and nodes before returning to the venous system by the thoracic duct. Under normal conditions, the entry of fluid and other materials into the interstitial space is balanced by outflow of the lymphatic fluid from the limb, which maintains standard volume. Lymphedema occurs when there is an interruption or obstruction of the lymphatic system that causes an accumulation of fluid in the limb. A healthy adult has approximately 600-700 lymph nodes.

6. Lymphedema Lymphedema is an abnormal accumulation of high-protein concentrated fluid, usually in the arms and legs. Lymphedema is a swelling of the extremities or rarely the face and genitalia, due to malfunction of the lymphatic system as obstruction of lymphatic vessels Lymphedema is described as an abnormal collection of protein, edema, fibrosis and chronic inflammation.

7. Risk Factor (Secondary): Surgery Any surgery that dissects or removes lymph nodes increases the risk of lymphedema by impairing the lymph flow. Common cancers that may require surgical alterations of the lymph nodes include breast cancer, head and neck, prostate, testicular, bladder, or colon cancer. Surgical disruption of lymphatic system Vascular surgery

8. Risk Factor: Radiation Radiation therapy to the axillary or groin region around the lymph node can cause fibrosis and scarring of the tissue and therefore cause lymphedema to occur Risk Factor: Lymphedema and Breast Cancer It is estimated that 15-20% of patients with breast cancer will experience lymphedema.

9. Types of Lymphedema 1- Pitting edema Short duration edema Finger indentation of the skin 2- Brawny edema Tissue feels hard upon palpation Indicates fibrotic changes 3- Weeping Fluid leaks, wound healing is impaired Occurs mostly in the lower extremities

10. Stages of lymphedema Stage I Considered reversible There is lower than 3 cm difference between extremities. Stage II Considered irreversible There is 3 to 5 cm difference between extremities. Stage III Tissues are hard and may have cartilage formation developing. There is more than 5 cm difference between extremities.

11. Signs and symptoms Painless swelling of the arms or legs, which may get worse during the day and better at night. Redness, Warmth or achiness in the extremity. A feeling of tightness, heaviness, tingling, numbness, or weakness in the affected extremity. Bracelets, rings, or shoes may become tight. A 2 cm difference between extremities is a general classification. Tends to occur distal to proximal Increased pigmentation/superficial veins Secondary cellulitis

12. Measurement Methods 1. Water displacement – “gold standard” 2. Circumference 3. Perometry 4. Bioelectrical impedance

13. 1- Water displacement – “gold standard2- Circumference

14. Upper limb circumference. lower limb circumference.

15. 3- Perometry4- Bioelectrical impedance

16. I stage of Lymphedema Recommendations about change of a way of life The elastic compression Preventive and medical rehabilitation programs  Magnetic stimulation,  Pneumo-compression,  Magnetic laser therapy,  Pulse matrix laser therapy,  Balneotherapy ( (العلاج بالمياه المعدني  Thalassotherapy. العلاج بمياه البحر))

17. II stage of Lymphedema recommendations about change of a way of life compression therapy courses of medicamentous treatment are spent 2 times a year. medical rehabilitation programs:  a pneumocompression,  magnetic laser therapy or pulse matrix laser therapy  magnetic stimulation,  cryotherapy, balneotherapy, thalassotherapy,  manual lymph drainage and bandaging of the limb.

18. III stage of Lymphedema to change of a way of life, compression therapy, Medical rehabilitation programs (a pneumo-compression, magnetic laser therapy, magnetic stimulation, pulse laser therapy, cryotherapy, balneotherapy, thalassotherapy, manual lymph drainage and bandaging of the limb) are spent 2-3 times a year. Medicamentous treatment is spent by courses for 4-6 months and includes preventive appointment of the prolonged antibiotics for prevention of relapses of an erysipelatous inflammation.

19. IV stage of Lymphedema patients accept surgical treatment with carrying out of conservative preoperative preparation. postoperative rehabilitation with use specified physiotherapeutic and medicamentous methods.

20. Physical Therapy Components Of A Decongestive Lymphatic Therapy Program 1. Elevation 2. Manual lymphatic drainage 3. Compression bandaging and Garment 4. Exercise 5. Pneumatic Pumps 6. Electro modalities 7. Skin care 8. Daily living precautions

21. 1- Elevation *Elevate the involved limb when using a sequential compression pump *Elevate limb when sleeping, resting, and during sedentary activities *Compressive bandages or garment should be worn during periods of elevation

22. 2- Manual Lymphatic Drainage * Slow, very light, repetitive stroking and circular massage movements performed in a specific sequence, limb elevated whenever possible. * Proximal congestion in the trunk, groin, buttock, or axilla is cleared first. * Direction of massage is towards specific lymph nodes. * Usually involves distal to proximal stroking.

23. 3- Compression bandaging and Garment. * Compression Garments. * Once a manageable size has been achieved from wrapping, a compression stocking may be worn to maintain the size and prevent increased swelling. * Bandages may be applied to increase tissue pressure and counteract the elastic insufficiency of the connective tissue.

24. 4- Exercise * Active range of motion, stretching, circulatory and low-intensity resistance exercise is incorporated with manual drainage techniques. * Exercises should be performed with compressive bandages or garment * Exercises are performed in a specific sequence, often with the limb elevated * Low-intensity cardiovascular/pulmonary endurance activities. * Deep breathing and relaxation.

25. 5-

26. 6- Electro modalities Ultrasound : Pulsed, 0.1-0.3 W/cm2; for 5-8 minutes Pulsed ultrasound at a lower intensity will produce mechanical and non thermal effects that will soften fibrotic tissues. Ultrasound may be used for its fibrinolitic effects on lymphostatic fibrosis.

27. 7- Good skin care Keep the skin clean and dry Apply moisturizer daily Protect skin with sunscreen and insect repellant Use care with razors Wear gloves during activities Avoid extreme temperatures

28. Daily living precautions No blood draws, finger pricks for blood sugar testing, IVs, blood pressures, or injections should be taken on the affected extremity. Anything that may cause pressure needs to be avoided including: *Blood pressure cuffs *Tourniquets *Tight clothes (waist bands, bra straps, socks) This constricts collateral circulation

29. Precautions Heat may cause vasodilatation, which causes more fluid to move from the blood vessels into the tissues. Avoid hot showers and saunas. Cold may cause rebound swelling or chapped skin Air travel more than 2 hours increases the risk of swelling because of continuous reduction of cabin pressure. It is recommended to wear a compression stocking while flying. Avoid carrying a purse, briefcase, or other heavy item with the affected extremity. If the lower extremity is affected, avoid standing or sitting for long periods of time and do not cross legs.

30. Thank you