1. Improving the lives of people living with cancer

2. Superior Tracking and Pushability
Improved Tumor Fill
Reduced Non-Target Embolization
Simple Integration
Superior tracking and pushability
Improved tumor fill
Reduced Non-Target Embolization
Simple integration

3. Superior Tracking & Pushability
Photos courtesy of Aaron Fischman, MD

4. Problems to be Solved Embolization with a Standard Microcatheter
Tumor
Stomach
Liver
Intestine *
Injection with
Standard Catheter
>
High
Pressure
Flow towards
healthy tissues
Embolization with a Standard Microcatheter
The drug/embolic agent is injected under high arterial pressure
Drug/embolic agent delivery is random and not reproducible
Does not optimally fill the tumor
Travels to healthy tissue via antegrade and retrograde flow

5. Deliver embolic agents more confidently
Low Pressure Embolization (LPE)
LPE represents a paradigm
shift in standard drug-delivery for tumor therapy.
Deliver embolic agents more confidently
and with more control.
LPE represents a paradigm shift in standard drug-delivery for tumor therapy. Deliver embolic agents more confidently and with more control.

6. Low Pressure Embolization (LPE)*
>
Lower
Flow redirection
toward tumor
Embolization with a Sniper Microcatheter
The balloon occludes the artery resulting in low pressure near the tumor
Branch arteries are redirected and flow toward the low pressure
Drug/embolic agent flows exclusively into the tumor since it has the lowest pressure
Drug reaches tumor vessels
Drug does not flow toward healthy tissue

7. Improved Tumor Fill with LPE
Sniper Microcatheter with Y90
Standard Microcatheter w/ Tc-99m MAA
Post-procedure SPECT Scan
Post-procedure SPECT Scan
Infusion with a standard high flow microcatheter results in preferential Tc-99m MAA deposition along the periphery of the tumor.
Infusion with an Embolx Sniper Microcathteter yields uniform distribution of Y90 throughout entire tumor.
Photos courtesy of Brian Kouri, MD

8. Schedule a Clinical Demonstration.
Speak to an Embolx Representive
to Learn More.
Embolx, Inc | 740 San Aleso Ave | Sunnyvale, CA 94085

9. Improved Tumor Fill with LPE
Standard
Catheter
Embosphere µ
Embozene 400µ
Embozene 250µ
InfusionType
Study concluded that 2.4 X the amount of embolic agents are collected with Sniper as compared to a standard catheter.
NSF Funded Animal Study

10. Reduced Non-target Flow with LPE
Sniper®
Balloon
Tumor
Artery
Only Tumor Artery is visible,
all other arteries flow toward
the tumor when the
Sniper® balloon is inflated
Only Tumor Artery is visible,
all other arteries flow toward
the tumor when the
Sniper® balloon is inflated
Pseudo-Tumor
Low Pressure Zone
Right Hepatic Arteries
Left
Hepatic
Arteries
Particle
Collection
Tumor Artery
All arteries are visible
NSF Funded study conducted by at UCSD by Dr. Steve Rose, Chief of Interventional Oncology, UCSD Medical Center

11. Simple Integration
High performance with comparable pricing to standard microcatheters
Compatible with 5Fr diagnostic/guide catheter
Easy to use
Requires no additional accessories
High performance with comparable pricing to standard microcatheters
Compatible with 5Fr diagnostic/guide catheter
Easy to use
Requires no additional accessories

12. What Experts are Saying:
"Bottom line, fixed temporary occlusion balloons and dynamic anti-reflux devices for transarterial embolization of liver tumors appear to simultaneously improve both safety and efficacy.”
Steven C. Rose, MD FSIR
Director of Interventional Oncology
University of California, San Diego, CA

13. What Experts are Saying:
"Manipulating blood pressure and flow to improve the tumor-killing effects of embolization therapies is a promising new technique. Using an occlusion balloon catheter has the potential of not only improving outcomes, but also simplifying the treatment technique to make this option available to more patients and doctors."
Daniel Sze, MD PhD | Professor, Interventional Radiology
Stanford University Medical Center
Daniel Sze, MD PhD | Professor, Interventional Radiology
Stanford University Medical Center

14. Schedule a Clinical Demonstration.
Speak to an Embolx Representive
to Learn More.
Embolx, Inc | 740 San Aleso Ave | Sunnyvale, CA 94085