1. Psoriatic Arthritis Workshop OMERACT 7 Steering Committee Dafna Gladman, Philip Mease, Gerald Krueger, Désirée van der Heijde, Christian Antoni, Philip Helliwell, Arthur Kavanaugh, Peter Nash, Christopher Ritchlin, Vibeke Strand, William Taylor

2. PsA Workshop OMERACT 7 u Identify domains to be included in clinical trials of PsA u Develop a core set of domains u Identify instruments to be used for the domains. u Develop a research agenda. Objectives

3. PsA Workshop OMERACT 7 u Review of assessment tools in PsA. u Delphi exercise through CASPAR/GRAPPA. u Nominal group process through GRAPPA. u OMERACT 7

4. PsA Workshop OMERACT 7 u Review of process. u Review of domains identified in previous iterations. u Review of instruments used in clinical trials in PsA and psoriasis. u Review of radiographic methods used in PsA. u Break out groups.

5. Results of Delphi Exercise DMARD Active Joint Count Pain Patient global X-ray damage Physical function Acute Phase Reactant Quality of Life Physician global Skin disease Damaged Joint Count Enthesitis Dactylitis Morning stiffness Lumbar mobility Work disability Work limitation Performance Tendonitis Cervical mobility Thoracic mobility MRI/US Sacroiliac signs Fatigue Extra-skeletal Sleep Utility indices

7. PsA Workshop OMERACT 7 u Review of results from breakout groups. u Review of discussion from breakout groups. u Analysis of instruments used in two drug trials in PsA. u Voting on domains to be included in clinical trials in PsA.

8. Results of vote on Domains in PsA

9. PsA Workshop Domains in PsA ItemScore Joint activity Patient Global all 3 components Pain assessment Physical function Skin disease Quality of Life Structural damage Acute Phase Reactant Axial involvement Participation Enthesitis 99% 96% 76% 94% 91% 86% 78% 66% 64% 61% 60%

10. PsA Workshop Domains in PsA ItemScore Fatigue Dactylitis Physician Global Tissue histology MRI Morning Stiffness Damage joint count 48% 41% 38% 34% 25% 20%

11. PsA Workshop Research Agenda u Identify optimal joint count. u Develop instrument for patient global to incorporate skin and joint question. u Identify optimal Skin assessment. u Develop tools to define structural damage. u Develop instruments for Axial assessment. u Develop a tool for the assessment of participation. u Develop instruments for the assessment of Enthesitis.

12. PsA Workshop Research Agenda u Develop tools for the assessment Dactylitis. u Imaging modalities to assess inflammation and damage. u Develop Composite responder indices. u Differential tissue response to therapies. u Study methods to evaluate Fatigue in PsA.