1. Module One Assignment Professor Phil Warner

2. Module One Assignment: ‘Translation of New Medicinal Products to the Clinic ’ This assignment intends to demonstrate that you can meet the following module learning outcomes: demonstrate a critical awareness of translational medicine approaches currently being adopted in academia and industry demonstrate the ability to search, integrate and appraise appropriate sources of scientific information through written coursework

3. Module One Assignment Select a disease of from the list provided and then choose the paper from the list appropriate to that disease to help you focus your study Review the incidence, pathology, clinical symptoms and currently available treatments Discuss the possible limitations of currently available treatments, such as side-effects, costs, availability, treatment-refractory patients etc.

4. Module One Assignment Describe ongoing initiatives for improved treatment options, such as novel drug targets, novel therapies currently in development etc. Critically assess whether the new treatments in development will offer improved treatment options

5. Module One Assignment Guide to length and presentation: Maximum 2500 words (excluding abstract and references) Typed in minimum of 12 pt font and using at least 1.5 spacing

6. Module One Assignment DEADLINE: 9.30 am on Monday 2nd November 2009

7. Module One Assignment DELIVER HARD COPY to your ICRI campus Submit as a Word document to Turnitin on Blackboard (via ‘Assignments’ button > Module 1 assignment submission > view/complete). Final electronic submission must be the same as the hard copy. You have the opportunity to view your Turnitin report and make multiple submissions but you will only receive a report once in any 24 hour period.

8. Penalties A sliding penalty factor will be applied to all work handed in after the deadline. 10% of the final mark will be subtracted for each day beyond the deadline. If work is handed in more than five days after the deadline no mark will be given. Late submission of work will only go un- penalised when serious mitigating circumstances occur, such as would be supported by a medical doctor’s certificate. In such cases certificates must be presented as soon as practicable.

9. Plagiarism Plagiarism is classed as an academic offence because the ethos of Higher Education in the UK is one of learning and development rather than the repetition of other people’s work. Guidelines on plagiarism have already been provided, but if at any time you are in doubt about what constitutes cheating or plagiarism, and particularly if you have any doubt about how to reference material properly, please consult your Course Director, supervisor or personal tutor.

10. Marking Scheme Review the incidence, pathology, clinical symptoms and currently available treatments (20 marks) Discuss the possible limitations of currently available treatments, such as side-effects, costs, availability, treatment-refractory patients etc (10 marks) Describe ongoing initiatives for improved treatment options, such as novel drug targets, novel therapies currently in development etc (20 marks)

11. Marking Scheme Critically assess whether the new treatments in development will offer improved treatment options (10 marks) Presentation (15 marks) Marks are approximately equally split if the following features are demonstrated: Appropriate font style and size Good spacing of text, paragraphs and use of justification of text Good use of Titles, subtitles

12. Marking Scheme Appropriate use of figures and tables, with their reference in main text Appropriate use of figure legends, table legends, labels Good general English in terms of spelling and punctuation Use of correct tense Appropriate use of terminology (not too basic, but with appropriate definition where necessary A good ‘flow’ of English and logical structure to the assignment

13. Marking Scheme References (15 marks) Marks will be awarded through demonstration of use of an appropriate selection of sources; correct citation in main text; and appropriately styled detailed list of sources at the end of the document Abstract (10 marks) Marks will be awarded for giving a clear, well-written summary of your essay, limited to 200 words.

14. The Subject Areas HIV / AIDS Breast Cancer Diabetes Asthma Leukaemia

15. Relevant papers. These are provided as PDFs