1. WG on Computational Methods

2. State of the WG Sought to clarify notion of “multi-scale” modeling methods (book published on spatial multi-scale modeling) Tried to connect with medical communities Series of webinars Two workshops organized by co-leads

3. Current Interests of participants (17) Parameter estimation under uncertainty Model validation vs. data requirements Peer confidence in models (data-based) Dynamic vs. static modeling Mixed deterministic=stochastic modeling Formal modeling methods (theorem-based) Create a wiki-based tutorial Multi-scale model uncertainty propagation

4. Relation b/t genotypic & phenotypic modeling Model estimation and data requirements Exploration of simulated “big data”