1. Introduction Erik Segerdell Oregon Health & Science University RCN Meeting  NESCent  25 February 2011

2. XAO describes the anatomy and development of the African frog Xenopus Used to annotate and search for gene expression patterns in Xenbase (www.xenbase.org)www.xenbase.org OBO Foundry ontology, edited in OBO-Edit Anatomical systems, cell and tissue types classified according to Common Anatomy Reference Ontology (CARO) Lineage of tissues represented by develops from relationships, start and end stages Xenopus Anatomy Ontology

4. Eagle-i: a prototype of a biomedical research resource discovery network Data model designed in CMAP, implemented in Protégé Re-use/coordination of existing terminologies Upcoming challenges: enhancement of genotype and phenotype representation eagle-i dx.doi.org/10.1038/npre.2010.5176.1

5. RCN Ontology Coordination Help integrate ontologies at a high level as per the needs of the working groups and recommendations of the Advisory Board Advise on best practices Provide a ‘help desk’ function to new groups who are developing ontologies Help with RCN website administration