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Titration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase Inhibitors Patricia G. Cruz,

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Presentation on theme: "Titration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase Inhibitors Patricia G. Cruz,"— Presentation transcript:

1 Titration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase Inhibitors Patricia G. Cruz, Douglas S. Auld, Pamela J. Schultz, Scott Lovell, Kevin P. Battaile, Ryan MacArthur, Min Shen, Giselle Tamayo- Castillo, James Inglese, David H. Sherman Chemistry & Biology Volume 18, Issue 11, Pages 1442-1452 (November 2011) DOI: 10.1016/j.chembiol.2011.08.011 Copyright © 2011 Elsevier Ltd Terms and Conditions Terms and Conditions

2 Figure 1 Chemistry & Biology 2011 18, 1442-1452DOI: (10.1016/j.chembiol.2011.08.011) Copyright © 2011 Elsevier Ltd Terms and Conditions Terms and Conditions

3 Figure 2 Chemistry & Biology 2011 18, 1442-1452DOI: (10.1016/j.chembiol.2011.08.011) Copyright © 2011 Elsevier Ltd Terms and Conditions Terms and Conditions

4 Figure 3 Chemistry & Biology 2011 18, 1442-1452DOI: (10.1016/j.chembiol.2011.08.011) Copyright © 2011 Elsevier Ltd Terms and Conditions Terms and Conditions

5 Figure 4 Chemistry & Biology 2011 18, 1442-1452DOI: (10.1016/j.chembiol.2011.08.011) Copyright © 2011 Elsevier Ltd Terms and Conditions Terms and Conditions

6 Figure 5 Chemistry & Biology 2011 18, 1442-1452DOI: (10.1016/j.chembiol.2011.08.011) Copyright © 2011 Elsevier Ltd Terms and Conditions Terms and Conditions

7 Figure 6 Chemistry & Biology 2011 18, 1442-1452DOI: (10.1016/j.chembiol.2011.08.011) Copyright © 2011 Elsevier Ltd Terms and Conditions Terms and Conditions

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