1. Standard Process Cod Liver Oil
Thank you all for taking the time to be here today. I am excited to present information today on the new CLO. CLO was actually an integral part of the SP line for many years. We are all very happy to welcome it back into the line.
These statements have not been evaluated by the Food & Drug Administration. Product is not intended to diagnose, treat, cure or prevent any diseases. Statements made are independent of Standard Process, Inc.

2. A-F Betafood – 1950’s
Note on the label of this early box of A&F Betafood you’ll see - Fish Liver Lipoids.
Dr. Royal lee used CLO as a primary ingredient for the vitamins A , D & F complex factors in many products including both Catalyn and A-F Betafood.
Because the CLO sources were not always 100 percent reliable or attainable. SP started using more Flax oils as a source of vitamin F

3. Agenda History of Cod Liver Oil
Detail of new Standard Process Cod Liver Oil
Vitamins A , D, F & Cod Liver Oil
Studies supporting the use of Cod Liver Oil
Review of supportive protocols
We will go through a brief look back at CLO and what Dr. Royal had to say about it
I will give some detail about the new SP CLO and what makes it unique in today’s market
We will touch on the various vitamins associated with CLO and also how to position it with the other SP oils we currently have in the product line.
We will also look at where CLO will be an excellent addition to patient support programs. Some of the protocols are based on the research we will look at and others are guidelines meant to give you thoughts as to where you might include them with your patients

4. The Daily Gleaner - London England Monday November 4th 1901
“Two Hundred years of experience has proven that there is no substitute for Cod Liver Oil. The greatest scientists in the world have never been able to produce a substitute for it. The most eminent physicians in Europe and America have spent years in a vain attempt to produce artificially a preparation that would take the place of Cod Liver Oil.”
SCOTT & BOWNE, Mfg chemist New York
This is part of a quote from a newspaper article that was published in The article goes on to talk about how several companies were trying to produce synthetic substitutes to Cod Liver Oil with no luck.
This is a testament to how long CLO has been used as a nutritional supplement and also how long companies have tried to reproduce an artificial substitute for the real thing.

5. These are examples of ads that go way back showing how vital CLO was even back then.
Note the old sign in the back from 1935 advertising that the vitamin A content in a teaspoon CLO is equivalent to 5.5 quarts of milk, a pound of butter or 9 eggs!
They would actually use CLO as a topping for cattle, horse and pig feed

6. Dr. Royal Lee on Cod Liver Oil
“All natural vitamins are complexes. Natural vitamin A
contains a special fat soluble synergist that
physiologically lowers high blood
pressure just as natural cod liver oil
contains a synergist of vitamin D that
promotes the assimilation of calcium by
the body cells, whereas the pure
vitamin D will rob the cells of calcium.”
Address to the American Academy of Applied Nutrition
Huntington Hotel, Pasadena, California. May 24, 1953
Dr. Lee was pointing to the fact that Vitamin A from specific sources, in this case from kidney, has a special effect on lowering blood pressure. Just as CLO with its naturally occurring vitamin D, also has it’s natural synergist vitamin F, the essential unsaturated fatty acid. A critical function of these two vitamins in CLO is to work in combination in making calcium available to the cells of the body.
Keep in mind most patients are just supplementing using vitamin D alone (cholecalciferol) and are missing the critical vitamin F factors and the ability to have ionizable calcium available for the immune system.

7. Vitamin News
“It would seem that we are not justified in considering rat units of Vitamin D in irradiated ergosterol as being equivalent to the same number of rat units of Vitamin D in cod liver oil as a curative or prophylactic remedy for rickets.”
Barnes, D. J., (Brady, M. J. and James, E. W., Comparative Value of Irradiated Ergosterol and Cod Liver Oil as a Prophylactic Antirachitic Agent When Given in Equivalent Dosage According to the Rat Unit of Vitamin D, American Journal of Diseases of Children, 39:45, 1930
Vitamin D factor in viosterol and cod liver oil are not identical. Ten times as many Vitamin D units in viosterol do not give as much protection as plain cod liver oil.
(Abstract of DeSanctic, Rudolph and Craig, J. D., A Five-Year Clinical Study of the Prophylactic Value of Antirachitic Agents, New York State Journal of Medicine 34:16, , 1934).
This early research is pointing to the fact that the different synthetic forms of D were failing compared to natural Cod Liver Oil.
Mostly looking at Vitamin D2 compared to natural D

8. Vitamin News (continued)
Researchers have shown that the natural sources of Vitamin D such as cod-liver oil, butter and yeast also contain potent forms of Vitamin F. It is this Vitamin F of cod liver oil that, no doubt, is responsible for the vast difference between the clinical performance of the cod liver oil and purified or synthetic Vitamin D (such as Viosterol), that is so well known today.
More early research identifying the sources of vitamin F as a critical component to the efficacy of CLO and other foods that contain the F factors

9. Dr. Royal Lee – Vitamin D Conversations in Nutrition April 1955
What do you think of vitamin D preparations such as cod liver oil?
Cod liver oil is the best form of all for vitamin D. If you get natural cod liver oil that has not been meddled with or altered or concentrated or enriched. It has been proven very emphatically because in treating surgical wounds they use cod liver oil to speed up healing and it won’t work if you don’t use the natural oil without any changes.
From Dr. Lee’s answer, you would certainly consider CLO as part of a post surgical protocol along with Chlorophyll and certainly a few other products depending on the type of surgery.
Most CLO products on the market have incredibly high levels of Vitamin D, this would indicate that synthetic D3 has been added in to fortify the product. Much of the Vitamin D on the market is striped of the natural vitamin A & D and then it is synthetically added back in to make a better label claim.

10. Dr. Royal Lee – Vitamin F Conversations in Nutrition April 1955
What can you tell us about vitamin F?
If you use natural cod liver oil, you get the two vitamins together ( D & F) and you never know they existed. But when you take them apart and take the synthetic D alone, then you are in trouble. Synthetic vitamin D has killed thousands of youngsters because it caused calcification of the kidneys and created a vitamin F deficiency.
We know that in nature vitamins work together in a synergistic way. Giving high doses of one specific vitamin factor can and will often cause imbalances in the system

11. Are Your Patients Getting Enough Vitamin A & D?
National Health and Nutrition Examination Survey (NHANES) data, at least 50 percent of people in the United States could be consuming less than the recommended daily allowance of vitamin A. NHANES data also suggests that almost all of us (90 percent) are deficient in vitamin D. Products like Cod Liver Oil, with or without additional supplementation, could help meet each
patient’s individual need.
As you can see the HANES research shows that most Americans are consuming less than 50% of the RDA for vitamin A and that 90% of the population is deficient in vitamin D. This really does point to the need for these vitamins more now than ever.
We know that much of the vitamin D deficiency is due to the fact the most people don’t get out in the sun anymore and if they do they have so much sun block on they don’t produce the free vitamin D that is available to them
Sun block with an SPF of only 8 will block 92.5% of the conversion of the oils on the skin to be converted to vitamin D and a sun block of 15 will block 99%. Most makeup that woman were have an SPF of between 8-15
Keep in mind that if someone is getting minutes of summer sunlight even in Cape Cod MA they are producing approximately 15,000 units of vitamin D The great thing about the sun is that your body destroys excess D so you will not become vitamin D intoxicated from sun exposure.
Of course we know that other problems from too much sun can occur, one of course is a buildup of too much calcium in the blood and it not being delivered to the tissues. So if you are going to be in the sun for long periods of time be sure you are taking enough Calcium Lactate and Cataplex F.
Some of the information regarding the conversion of vitamin D is from Michael Holick. He is a Phd, MD and is known as the vitamin D pioneer. He determined the mechanisms of how vitamin D is synthesized in the skin.

12. Dr. Royal Lee – Vitamin News
Vitamin F, the fat-soluble growth principle found associated with E, and acting to oppose the action of Vitamin D in maintaining calcium balance in the blood, appears to be the specific antidote for D poisoning. It is apparently present in cod liver oil and this would account for the great difference in toxicity of cod-liver oil D as compared to irradiated ergosterol.
Another quote from Dr. Lee showing how natural vitamins work together to maintain balance in the system.

13. Dr. Royal Lee – Vitamin News (continued)
Thus, if the diet is deficient in both fat-soluble vitamins A and D, as for instance when olive oil replaces cod liver oil, the following abnormalities develop…
Thickening of the gingival region
Hypertrophy of the sub-gingival epithelium, with the development of finger-like processes.
Irregular alignment of some of the teeth and tilting of the teeth in relation to the jaw
Irregular thickness of the periodontal membrane
What Dr. Lee is pointing out here is that CLO with its naturally occurring vitamins A & D, have a leg up on other oils like olive oil and other oils, that contain only omega oils but no other vitamin factors. In the case of Olive oil it is good oil and it is actually has some omega 3s and mainly omega 9s. But no vitamin factors

14. The Process
Short path distillation is a method which removes metals, PCBs and other toxins to below detectable levels for human consumption. There are different levels of Molecular distillation.
Standard Process Cod Liver Oil is not
bleached with clays and does not go
through a deodorization or an esterification process which will denature and refine oil as well as break down triglycerides and separate the fatty acids from glycerine
Molecular distillation is used for removing any heavy metal or PCB’s that often can be found especially in the oil from the liver. Standard Process’s CLO goes under a process called short path distillation. This technique is done in very high vacuum with reduced pressure. It is used specifically for compounds that are unstable at high temperatures. The advantage is that the heating temperature is considerably lower at reduced pressure than the boiling point of a liquid at standard pressure. Tuna Oil is not derived from liver so this is not an issue.
Most commercial oils go a step further in the Molecular distillation process - they actually heat the oil up to a liquid mixture and the vapors are condensed and collected as separated liquids. They can then extract DHA and EPA from the oil an add the DHA or EPA back in to make another oil in order for it to look more potent. This process can also strip out the naturally occurring vitamins A & D as well as the co-factors. The synthetic vitamins are in for added label claims of those vitamins, and omega 3s as we will see this on the next slide

15. Commercial Cod Liver Oil
Take note that the vitamin D content. It says from fish liver oils and D3. Which means this probably went through a high distillation process in order to add the D3 back into the natural oil. Oftentimes, you will also see abnormally high levels of EPA and DHA because through that heavy distillation process, they will add in extra EPA and DHA to make the oil look more substantial.

16. Natural Unrefined Cod Liver Oil Has More Than Just Retinyl Palmitate
The top green line is an HPLC of the Natural profile of vitamin A in SP Cod liver oil compared to a commercial brand.
Natural Cod liver oil contains a number of vitamin A esters. Most CLO oil manufacturers remove these esters during processing and just add back retinyl palmitate.
“Vitamin A is important for normal vision, gene expression, reproduction, embryonic development, growth, and immune function.”9
Vitamin A is required by eye for proper brain signaling related to vision.
Vitamin A is needed for healthy tear production in the eye.
Vitamin A is needed for normal retinal rod and cone cell functioning.
By interacting with receptors in a host of cells, retinoic acid regulates the production of molecules that are necessary for proper epithelial cell integrity throughout the body (skin keratins, enzymes, extracellular proteins, etc.).
Retinoic acid affects cytokine production, thus modulating T and B cell production.
Retinoic acid is needed to maintain natural killer cell levels and phagocyte activity in mouse macrophages (whether retinoic acid has this specific action in humans is not known).
B lymphocytes require retinol for their growth and differentiation, as well as for activity.*

17. Contains Naturally Occurring Coenzyme Q10 (CoQ10)
CoQ10 is a fat-soluble substance used in the body’s energy-generating processes. The minimal processing selected for Standard Process Cod Liver Oil has the beneficial effect of retaining CoQ10 from cod livers.
Another testament to our processing to be sure we are leaving in natural constituents in the oil is by seeing that SP’s CLO has naturally occurring COQ10.

18. Ålesund Norway – Cod liver oil capital
3 Cod species
No added vitamin A or D
Every batch tested for contaminants
Each serving is an excellent source of naturally occurring vitamins A and vitamin D complexes
Dr. David Barnes the head or research and Development went to Norway to inspect the processing plant that we chose to produce the Cod Liver oil. Its actually a small facility that take extra care with its process.

19. Standard Process Cod Liver Oil
A serving of Cod Liver Oil contains 1,000 mgs of oil, which is 3 perles. Looking at the label and seeing what appears to be a limited amount natural vitamins A & D, is much like looking at our Cataplex C, with each serving of Cataplex C being 600 mgs total, but containing only 17 mgs of Ascorbic acid.
Remember in Dr. Lee’s teaching that a vitamin complex is a wheel within wheels - don’t get caught up looking for the one isolated or synthetic factors like a chemist looking at a drug.
In fact like the tyrosinaise in cataplex C is very much like the vitamin F factors in CLO - they could be as important as any other component in CLO.

20. General Recommendations for Vitamin D
Minimum blood levels of vitamin D should be above 29 ng/mL and optimal between ng/mL
Supplementing with IU’s of vitamin D daily for two months should increase to within normal levels (this is not including all the other sources of D in the diet or sunshine)
Consider three Cataplex D and three CLO daily for two months
A maintenance dose of 1000 IU’s daily of vitamin D from all sources
It takes about 100 IU’s of D to raise the blood 1 ng/ml of vitamin D so if a patient has blood levels of ng/ml and you supplement with IU’s of D you should raise the D level to approximately 40 ng/ml it may take a month or two depending on all the other factors involved.
You might consider supplementing three Cataplex D a day which is 2,400 IU’s of D, 3 CLO per day is 120 IU’s of D. Plus you’re supplying the added vitamin A complex from both CLO and Cataplex D as well as the vitamin F from CLO.
For Maintenance: Six Catalyn has 624 IU’s of vitamin D. So Six Catalyn and three CLO daily will provide about 1000 IU’s of D and 3,540 IU’s of vitamin A daily or 70% of the RDA for vitamin A complex
Toxic levels of supplementing vitamin D can occur by taking 10,000 IU’s a day for more than 6 months.
The RDA (for adults) for Vitamin A is 10,000 IU per day. This is the total recommended daily intake of Vitamin A (including from dietary sources) for adults. Much of this dosage will be derived from the diet, therefore a suggested range of Vitamin A supplementation for healthy people is 5,000 IU per day for men and 2,500 IU per day for women.
Toxic Dosages
Women should not consume more than 10,000 IU of Vitamin A per day during Pregnancy as amounts above this level have been shown (especially during the first seven weeks of pregnancy) to cause Birth Defects in approximately 2% of pregnancy women. It may be prudent to ensure that daily Vitamin A consumption does not exceed 5,000 IU during Pregnancy. It may be advisable for pregnant women to avoid Vitamin A supplementation altogether and, if necessary, use Beta-Carotene supplements instead (as Beta-Carotene is incapable of causing Vitamin A toxicity).
Adults who consume 50,000 IU or more per day for long periods (several years) may experience the symptoms of Vitamin A toxicity. Smaller daily dosages can cause toxicity in people with Cirrhosis, Hepatitis.

21. The Different Levels of Vitamins A & D and EPA & DHA
Product:
Cod Liver Oil
Calamari Omega-3 Liquid
Tuna Omega-3 Oil
Tuna Omega-3 Chewable
Linum B6 (630 mg of flaxseed oil per serving)
Form
perle (3/day)
liquid (1 tsp./day)
perle (4/day)
Vitamin A
1,140 IU NA
Vitamin D
120 IU
200 IU
EPA/serving
210 mg
400 mg
120 mg
100 mg
DHA/serving
300 mg
800 mg
600 mg
500 mg
Alpha-linolenic acid/serving
~346 mg
If you are looking to supply high levels of EPA and DHA, then you would want to consider adding in either Tuna or Calamari Oil to a protocol included with CLO. The reason I’m telling you this is because by supplementing too much CLO with other vitamin A supplements being provided, you want to be aware not to supplement too much Vitamin A especially during pregnancy.

22. Research on Cod Liver Oil
The next slides will focus on research and protocols based on research along with other products that should be considered adjunctive to CLO.
Research on Cod Liver Oil

23. CLO during pregnancy Use of cod liver oil during pregnancy is
associated with lower risk of Type I diabetes in the offspring.
This effect was found only in mothers taking cod liver oil, not
in mothers taking multivitamin supplements.
Cod liver oil taken by nursing mothers improves the breast milk by increasing the amount of fatty acids, which promotes brain development, and the amount of vitamin A, which helps prevent infections, but the level of vitamin D is unchanged.
Stene, L. C., et al. Use of cod liver oil during pregnancy associated with lower
risk of Type I diabetes in the offspring. Diabetologia. 43(9): , 2000
This was published in 2000 in Diabetologia

24. Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study
Use of cod liver oil in the first year of life was associated with a significantly lower risk of type 1 diabetes (adjusted odds ratio: 0.74; 95% CI: 0.56, 0.99). Cod liver oil may reduce the risk of type 1 diabetes, perhaps through the anti-inflammatory effects of long-chain n-3 fatty acids.
American Journal of Clinical Nutrition. 78(6): , 2003
From the American Journal of Clinical Nutrition pointing to the benefits of CLO for diabetics.

25. This program should be continued through out pregnancy
Pre-Natal Protocol
Cod Liver Oil per day
Vitamins A & D complexes for bone building and bone development
Catalyn per day
A whole food multi-vitamin and mineral concentrate with 14 different whole foods
Folic Acid B per day
For prevention of neural tube defects
Calcifood Wafers or Powder per day (1 tbls powder = 9 wafers)
Source of bone building protein and minerals from bone meal and veal bone, especially methionine, lysine and tryptophan first amino acids lost in cooking. Consider Calcium lactate if need for ionizable calcium
SP Green Food per day
Excellent source of cruciferous vegetables , kale and Brussels sprouts, which provide both Lutein and Zeaxanthin; Provides overall cellular health
Immuplex per day
Fortifies immune system with support from spleen, thymus, and liver; also excellent source of zinc and folate
This program should be continued through out pregnancy
Here is what could be considered for a good pre-natal support program and also post program. Of course this might be altered depending on the specific needs of the mother
Folic Acid lowers (by approximately 70%) the risk of Neural Tube Birth Defects pre Pregnancy (by increasing the production of endogenous Nucleic Acids that are in strong demand during Pregnancy)
Desiccated Spleen has two very important immune modulaters, splenopentin and Tufstin
Splenopentin is a five-Amino Acid (Pentapeptide Oligopeptide) component (fraction) of the Spleen. Splenopentin is the active component of the Thymic Hormone, Thymopoietin
Tuftsin is an endogenous Tetrapeptide (i.e. it contains four Amino Acids within its molecular structure) produced by the Spleen. Tuftsin stimulates various aspects of the Immune System:
- Tuftsin supports the activity of Macrophages.
- Tuftsin supports the activity of T-Lymphocytes.
This would equate to about 3925 IU’s of vitamin A (just over half the daily dose recommended)

26. Low vitamin D status linked to higher risk of diabetes
Deficiency in vitamin D may be associated with an increased risk of developing type 1 diabetes, according to new research. The study published in Diabetologia finds a correlation between serum levels of vitamin D3 and subsequent incidence of Type 1 diabetes.
Led by Dr. Cedric Garland and colleagues from the University of California, San Diego, USA, the team performed a six year analysis of nearly 2,000 people — finding higher levels of serum vitamin D3, known as 25-hydroxyvitamin D [25(OH)D], are associated with a lower incidence of the disease. Therefore a preventive roll of vitamin D is suggested
Diabetologia volume 55, issue 12, pags , November 2012
Newer research

27. Diabetes Support Protocol
Cod Liver Oil per day
Natural D source and A as well as EFA’s
Diaplex per day
Pancreas pmg & cytosol extract, pea vine for E complex buckwheat juice for capillary support
Gymnema per day
Improve the ability of insulin to lower blood sugar, and repair beta cells in the pancreas generally improving blood sugar control
Zinc Liver ChelateTM per day
Zinc increases cellular glucose assimilation and glucose effectiveness
Cataplex GTF per day
Chromium supports blood sugar regulation and aides the interaction of glucose, insulin, and glucagon. It improves the uptake of glucose to cells where it can be used to produce energy
Diaplex is a wonderful long-term support product with pancreatic support, vitamin A from kidney, chromium. Diaplex is a good source of vitamin F and vitamin E from pea vine. We all know about chromium and insulin but many don’t know that Vitamin E complex will assist insulin use by making cell membranes more permeable or receptive to insulin, allowing more glucose into
cells. Glucose tolerance is improved and pancreatic beta cells are also protected.

28. Effect of CLO on Rheumatoid Arthritis
Patients with rheumatoid arthritis ingested 1 g of cod liver oil (one capsule) daily for 3 months. Decreases occurred in morning stiffness (52.4%), painful (42.7%) and swollen (40%) and pain intensity (67.5%). Ratings of "good" or "very good" were awarded by 68% of the patients for efficacy and by 95% for tolerabilityCod liver oil can be recommended for the treatment of rheumatoid arthritis.
National Library of Medicine Adv Ther 2002 Mar-Apr; 19 (2): 101-7

29. Rheumatoid Arthritis Support Protocol
Maintenance:
Cod Liver Oil per day
Source of vitamin F factors and DHA & EPA vitamin A & D complex all shown effective with these patients
Rumaplex per day
Multiple Rheumatoid support product also providing bone PMG for autoimmune factors involved
Organically Bound Minerals 3-6 per day
Supplies potassium and other alkaline ash minerals for bone development
Boswellia complex per day
Boswellia and Turmeric in the complex inhibit leukotrienes which help to reduce cellular inflammation
Acute add:
Thymex per day
Support phagocytic and lymphatic factors and inflammation
Rehmannia complex per day
Rehmannia and hemidesmus help control autoimmune activity and anti-inflammatory factors

30. New trial shows Cod Liver Oil can reduce the need for anti-inflammatory drugs without loss of pain-relief
The results of a five-year study show that Cod Liver Oil can reduce the amount of anti-inflammatory drugs taken by Rheumatoid Arthritis (RA) patients by over 30%.
Results showed that by taking Cod Liver Oil daily nearly 40% of patients were able to reduce their anti-inflammatory intake by over 30%. Most importantly this study showed that the reduction in intake of anti-inflammatory drugs in those taking the Cod Liver Oil supplements was not associated with any worsening of pain or disease activity.
This study offers hope to many Rheumatoid Arthritis patients for whom Cod Liver Oil supplements can offer a natural pain management treatment without the harmful side effects associated with the use of anti-inflammatory drugs.
1 Belch JJF, Nuki G, Galarraga B. et al. (2008) 'Cod Liver Oil (N-3 Fatty Acids) As a Non-Steroidal Anti-Inflammatory Drug Sparing Agent in Rheumatoid Arthritis' P.13: Discussion 2 Arthritis Care, The Impact of Arthritis Fact Sheet (July 2007) To download a copy of the full paper click here:
We all know that Cox 2 inhibitors like viox and Celebrex have had detrimental effects.

31. Patients on cod liver oil showed less pain and slightly less interference with their normal activities than patients on placebo
This study involved 26 osteoarthritis patients. Patients received 10 ml per day of either cod liver oil or an olive oil placebo plus their usual NSAID's daily for 6 months.
At the end of the 6 month period, the patients on cod liver oil showed less pain and less interference with their normal activities than patients on placebo, though the difference was not statistically significant.
Stammers, T., et al. Fish oil in osteoarthritis [letter]. Lancet. 2:503, 1989.

32. Omega-3 fatty acids (DHA and EPA) from cod liver oil reduced aggrecan-degrading enzymes and collagen-degrading enzymes in 86% of patients
Authors conclude that cod liver oil retards cartilage degeneration in osteoarthritis and reduces the factors that cause pain and inflammation in osteoarthritis patients.
Omega-3 fatty acids in the oil appear to switch off the aggrecan- and collagen-degrading enzymes that break down joint cartilage, slowing cartilage destruction and reducing inflammation, which lessens arthritic pain.
Caterson, B., et al. Arthritis and Rheumatism. Cardiff University, UK.

33. Cod liver oil intake during the previous week was associated with a 25% reduction in patients reporting intense pain and a 19% reduction in the number of patients reporting considerable/intense pain
The object of this study was to investigate the relationship between dietary supplementation of cod liver oil and the intensity of pain in people with musculoskeletal pain in a cross-sectional study.
The study suggests that people with musculoskeletal pain experience less pain if they take cod liver oil.
Eriksen, W., et al. Does dietary supplementation of cod liver oil mitigate
musculoskeletal pain? Eur J Clin Nutr. 50(10):689-93, 1996.

34. Inflammation/Pain Support Protocol
Cod Liver Oil per day
Chronic pain patients often have low Vitamin D levels and it is also a great source of Omega-3s for inflammation
Tuna Omega-3 Oil 4 per day
Excellent source of Omega-3 for anti-inflammatory effects
Boswellia Complex 3 per day
Inhibits inflammatory leukotrienes to reduce inflammation
Chlorophyll ComplexTM (chew perles) 3-6 per day
Has a neutralizing effect on the inflammatory aspects of gaunidine
Saligesic per day
High potency willow bark extract; very effective as an analgesic and anti-inflammatory
If nerve pain add Inositol Powder
- Inositol is known as a mild support for pain management
Initially I would recommend in acute cases of inflammation where you want to supply high levels of vitamins A & D as well as EPA & DHA, consider combining CLO and Tuna Oil or CLO and Calamari oil together. 6 perles of CLO contain 600 mg of DHA and 420 mg of EPA. Adding 4 Tuna Oil a day would supply another 300 mg of DHA and 120 mg of EPA
Inositol as a treatment for pain control was evaluated. The authors report an analgesic effect for inositol-1,2,6-triphosphate in this double-blind, randomized study of 24 patients undergoing cholecystectomy. Opioid analgesia requirements were significantly reduced when patients received a bolus inositol dose of 240 mg followed by 90 mg/hr for 24 hours. There were no side-effects reported with the bolus or maintenance infusions.

35. Cod liver oil reduced the number of new cavities by ½ compared with children who did not receive cod liver oil.
In this clinical study, children who received one tablespoon of cod liver oil per day for one year reduced the number of new cavities by ½ compared with children who did not receive cod liver oil.
McBeath, E. C., et al. The role of vitamin D in the control of
dental caries in children. Journal of Nutrition. 15:547–564, 1938.
This is truly a remarkable study that was done over 70 years ago. There were two orphanages in NYC that were picked to perform this. There were 105 kids that took part of this study

36. Children’s Support Protocol
Cod Liver Oil per day
For young children puncture perle
Vitamins A & D for bone building and bone development, Omega-3’s for brain and eye development
Catalyn or Cyrofood per day
Also consider Chewable Catalyn or Cyrofood Powder 1-2 tsp per day mix in blender with juice or smoothie if more fiber is desired
Catalyn for complete multivitamin and mineral supplement with enzyme source from 14 different whole foods for long term whole body support
Consider Calcifood wafers or powder which will further support bone, teeth, and related tissues; excellent sources of calcium, phosphorus, and protein (3-6 wafers per day, or 1-2 tsp of powder)
For hyper-active kids or if they are consuming too much sugar, consider Min-Tran and Cataplex B.

37. Cod Liver Oil may help to prevent (upper) Respiratory Tract Infections
The authors studied the effect of daily supplementation with lemon-flavored cod liver oil and a children's multivitamin-mineral supplement containing selenium on the number of pediatric visits by young, inner-city, Latino children from late autumn of 2002 through early spring of 2003.
The supplementation group had a statistically significant decrease in the mean number of upper respiratory tract visits over time; the medical records control group had no change in this parameter. The supplements were well tolerated; per parental report, 70% of children completed the 5- to 6-month course of cod liver oil.
Linday, L. A., et al. Effect of daily cod liver oil and a multivitamin-mineral supplement with selenium on upper respiratory tract pediatric visits by young, inner-city, Latino children: randomized pediatric sites. Ann Otol Rhinol Laryngol. 113(11): , 2004.

38. Upper Respiratory Support Protocol
Propholactic:
Cod Liver Oil per day
Vitamin A for the epithelial tissue support; Vitamin D for immune support and inflammation
Cataplex E per day
Vitamin E Complex with a naturally occurring source of selenium for tissue and connective tissue repair
Acute (add):
Congaplex per day
Source of alfalfa, mushrooms, carrots, Echinacea, and Calcium Lactate, which are nutrients specific to inflammatory states
Pneumotrophin PMG per day
A protomorphogen extract to support cellular DNA and RNA blueprint for repair of tissue
Euphrasia Complex per day
Contains Eyebright and Goldenseal for mucous membrane support and a natural trophorestorative
Cataplex ACP per day
Specific for immune and epithelial tissue support
Another benefit of CLO is with upper respiratory tract infections

39. Lemon-flavored cod liver oil and a multivitamin-mineral supplement for the secondary prevention of otitis media in young children
Giving a child a daily teaspoon of cod liver oil, which contains vitamins A and D and omega-3 fatty acids, together with a multivitamin tablet containing selenium, can help prevent otitis media, or reduce the amount of antibiotics needed to cure the condition.
This study provides preliminary evidence that some episodes of otitis media may be prevented and that the reliance on antibiotics may be reduced among young children by using nutritional supplements.
Linday, L. A., et al. Lemon-flavored cod liver oil and a multivitamin-mineral supplement for the secondary prevention of otitis media in young children: pilot research. Annals of Otology, Rhinology and Laryngology. 111(7 Part 1): , 2002.

40. Ear Infections (Acute) Protocol
 Cod Liver Oil per day
Source of Omega 3 fatty acids to support immune function
Congaplex per day
Support during acute infections
Carrots, alfalfa, mushrooms, Echinacea and CALCIUM LACTATE provide the nutrients and minerals needed during inflammatory states
Thymex per day
Help support healthy immune function and lymphatic drainage ( use 1-2 per hour during first 12 hours)
Cyruta per day
Supports epithelial as well as supports drainage in the body
Chewable Congaplex 9 per day
May be used with children one year or older, 9 tablets/day as the suggested starting dose for children under ten
The Cod liver perles can be punctured and put into juice or water for younger kids.
You obviously might consider adding more C Complex or Calcium lactate that is already contained in Congaplex.

41. Ear Infections (Chronic) Protocol
Cod Liver Oil 3 per day
Source of Omega 3 fatty acids to support immune function
Thymex per day
Help support healthy immune function; Help support lymphatic drainage
Zymex Wafers wafers per day
Support for healthy intestinal function
Supports normal pH in intestinal tract thus favoring the production of probiotics like acidophilus and bifido bacteria.
Immuplex Capsules 3 per day
Combines A , B12, C for immune support.
Contains bovine thymus, liver, and spleen tissue extracts to support healthy immune function
There are many protocols that might be considered here, but here is one basic one

42. The author reports that cod liver oil provides substantial relief for autism patients
I am using natural lipid soluble concentrated cis form of vitamin A in cod liver oil to bypass blocked G protein pathways and turn on these central retinoid receptors. In a few days, most of these children regain eye contact and some say their “box” of clear vision grows. After two months on vitamin-A treatment some of these children, when given a single dose of bethanechol [a drug related to acetlycholine, a substance that transmits nerve impulses] to stimulate pathways in the parasympathetic system in the gut, focus, laugh, concentrate, show a sense of humor and talk after 30 minutes, as if reconnected. This improves cognition, but they are still physically ill. When these children get the MMR vaccine, their vitamin A stores are depleted and they cannot compensate for blocked pathways. Lack of vitamin A, which has been called “the anti-infective agent,” leaves them immuno-suppressed. They lack cell-mediated immunity. T cell activation, important for long term immune memory, requires 14-hydroxy retro-retinol. On cod liver oil, the only natural source of this natural substance, the children get well.
One week ago my oldest son, who is gifted but dyslexic, had twelve neighborhood friends over for dinner. As I looked around the table, all of these children but one had dilated pupils. After two-and-one-half months of taking vitamin A and D in cod liver oil, my son announced, “I can read now! The letters don’t jump around on the page anymore!” He is able to focus and his handwriting has improved dramatically.
Megson, Mary, MD. Autism and Vaccinations. Weston A. Price Foundation.
This article points to the vitamin factors as an important constituent of the CLO complex

43. Cod Liver Oil and Breast Cancer
In an on-going case-control study, researchers found that increased vitamin D, either through sun exposure or dietary intake, reduced a woman's risk of breast cancer. Thus far, the team has reviewed data from 576 breast cancer cases identified through the Ontario Cancer Registry and 813 controls identified through randomly selected residential telephone calls. The cases were diagnosed between July 1, 2003 and June 30, 2004 and were aged 20 to 58 years. Women who worked an outdoor job, which would increase sun exposure, had a 40% reduction in the risk of breast cancer relative to those who had not (95% CI, ). Women who participated in outdoor activities had a reduced risk of breast cancer. Women who participated in more than 6 outdoor activities per week between the ages of 10 and 19 had a 45% risk reduction, relative to those who had fewer than four activities. Women who participated in more than 5 activities between the ages of 20 and 29 had a 28% reduced risk relative to those with fewer than 3 outdoor activities. Outdoor activities included both physically active and inactive ones, suggesting that it was a link to sun exposure rather than exercise. In terms of dietary intake, the researchers asked participants about cod liver oil. Women who took cod liver oil for 10 years or more had a 34% reduced risk, relative to those who did not (95% CI, ).
Potential reduction in breast cancer risk associated with vitamin D. 97th Annual
Meeting of the American Association for Cancer Research. Washington, D.C., USA. April 10, 2006.

44. Breast Cancer Prevention
Cod Liver Oil per day
Vitamins D and A with good source of EPA & DHA
Cruciferous CompleteTM per day
Kale and Brussels sprouts provide balance between 2/16 hydroxyestrogen ratio
Vitanox (tumeric , catechins) per day
Supports Phase II methylation
Protefood (methionine for methylation) per day
Provides essential amino acids and added methylation
Spanish Black Radish (especially with breast tenderness) 2 per day
Excellent source of sulfur up regulate phase II enzymes
Cataplex D ( consider if not exposed to sun) per day
To support phase 2 methylation of estrogens (methionine, choline, and COMT function)
Vitanox ( tumeric, catechins) - 1 to 2 per day
Protefood (methionine) - 1 bid w/meals
Soy bean lecithin or Choline - 1 to 2 per day w/meals
Spanish Blck Radish - 2 to 4 per day especially if woman is experiencing cyclical breast tenderness.
a few Brazil nuts per week (methionine)
a few servings of lentils a week (methionine, choline)

45. Additional Protocols

46. Building Bones / Osteoporosis Protocol
Cod Liver Oil per day
Vitamins A & D for bone building and EFA’s for inflammation and bone growth
Calcifood® Wafers (or powder) wafers (1 Tbls)
Source of bone building protein and minerals from bone meal and veal bone, especially methionine, lysine and tryptophan first amino acids lost in cooking
Cruciferous Complete daily
Great source of vitamin K important to activate inactive Calcitonin, enabling Calcitonin to transfer Calcium into the Bones
Cataplex® C daily
C complex is an essential cofactor of collagen formation in the bones
Ostrophin PMG daily
A good source of bone protomorphogen; also a foundational component of cartilage
This is a general protocol that can be considered – depending on the case, more products could be added or excluded

47. ARMD (Age-Related Macular Degeneration) Protocol
Bilberry 6000mg per day
May help to prevent Age-Related Macular Degeneration (ARMD) (due to the Anthocyanosides content of Bilberry)
Cod Liver Oil per day
Vitamin A for support for adaptation and aging in early stages of ARMD
Cruciferous CompleteTM per day
Excellent source of both Luten and Zeaxanthin from kale and Brussels sprouts; vitamin factors are found in these cruciferous vegetables, especially A, C, and E
Iplex® per day
Oculotrophin, A complexes from both kidney and liver, c complex from mushroom and buckwheat
There is research that supports the specific ingredients in these products as support for ARMD

48. General Immune Support Protocol
Cod Liver Oil per day
Kids 1-3 perles puncture perles if cannot swallow
Vitamin A & D are specific for immune support
Immuplex® per day
Fortifies immune system with support from spleen, thymus, and liver; also excellent source of zinc and folate
Congaplex® daily
At first sign of cold or flu, take 2 Congaplex® every hour for the first 48 hours
A source of ionizable calcium; Thymex for up-regulating T-cell activity, as well as A and C complex for added immune support
Thymex® (for flu and acute cases consider adding 1-2 per hour)
Up-regulates T-cell activity for immune response
Protocol to help prevent and fight chronic colds, flu, bronchitis, pneumonia, and more

49. Cardiovascular Support Protocol
Cod Liver Oil per day
Vitamin A to support healthy blood pressure levels; Omega-3s for anti-inflammatory factors
Cardio-Plus per day
Supplies heart protomorphogens, Vitamin C complex, and B-complex, as well as E2
Cataplex B per day
Supplies the Vitamin B-4 factors which are critical for motor-nerve conductivity
Cataplex G per day
Only add G if high blood pressure
Cataplex E2 (if they already had angina) 6-9 per day
Increases the oxygen-conserving factors
Calcium Lactate (if they already had angina) per day
Source of ionizable calcium for normal heart function
Vasculin would be considered for low blood pressure cases. This is a great cardiovascular support protocol. Depending on patients’ specific needs, dosages may be increased or decreased, but overall, these products will support many cardiovascular issues.

50. Dear Standard Process,
As a mother of two children and a personal trainer, I knew the importance of a quality omega 3 oil supplement, but your new Cod Liver Oil far surpassed my wildest expectations.
My eighteen year old son has dealt with cystic acne for the last four years. Dealing with the discomfort and self-image issues have been a struggle for him. After speaking with a dermatologist, and against my better judgment, we had considered prescription medication for this condition. Although less than two weeks have passed since he first started taking 6 Cod Liver Oil perles per day, we noticed significant improvement within a few days. The inflammation and redness have since disappeared and his skin is well into the healing process.
No other changes were made to my son’s daily routine which tells me the results we have seen in such a short time have come from Standard Process Cod Liver Oil. Thank you again for your commitment to providing another exceptional supplement…Cod Liver Oil!
Lisa Bennett, BS, CPT

51. Dr. Stuart White on Cod Liver Oil
“This product rewrites the rumors about Cod Liver Oil - it tastes terrific and it feels even better! No burning in the throat from rancidity - I don’t know how SP does it but the product renews the choice to utilize this remarkable food and give clinicians new horsepower in modulating DHA dependent mental performance.”
Stuart first tried this product a seminar in Cleveland and was amazed the way he felt within a few minutes of tasting the product.
I would add to his comment by saying that CLO is a great source of not only DHA & EPA but also vitamin A complex and natural source vitamin D complex with the built in F factors that are dependant on the proper utilization of both vitamin D and Calcium

52. Recap
Cod Liver Oil should be considered as a foundational support for many different nutritional programs
There is no other natural source that combines such wonderful blends of vitamins A , D & F as well as the Omega 3s as in Standard Process Cod Liver Oil

53. Questions?