2. Improving the pig’s immune status, productivity and efficiency by enhancing gut health
Rainer Rauch
4Mix International /

3. Overview Anatomy and digestion Metabolic Efficiency
How do we maximise Metabolic Efficiency?

4. Anatomy and digestion The main parts of the digestive tract 1. Stomach
2. Small Intestine
3. Cecum/Large Intestine
4. Liver (and associated organs)

5. Anatomy and digestion 1. Stomach
Secretion of enzymes and hydrochloric acid
pH = approx 2
Main enzymes = proteolytic (protein digestion)
Low pH important for
Partial / total eradication of microbes
Hydrolysis of proteins
To optimise pH-dependant protease enzyme function

6. Protein digestion in stomach
Acid
Acid dependant proteolytic enzymes

7. Small Intestine 2. Small Intestine
Alkaline secretions results in ~ neutral pH
Digestion of smaller protein chains (polypeptides) into amino acids
Absorption of amino acids
Bile secretion to emulsify fats, similar to detergent action (break apart globules to allow for enzyme attack)
~ neutral pH
~ neutral pH dependant protease enzymes

8. Cecum/ Large Intestine
Fermentation chamber
No enzyme secretion
therefore enzyme activity due to “carry over” from small intestine or microbial enzyme production
Similar in many ways to rumen
Microbial fermentation = 8-16% of digestion in pig
A low protein digestibility in the stomach / small intestine can lead to higher protein levels in the large intestine and an “E. coli friendly” environment
E. coli has been related to oedema disease

9. Liver 4. Liver Metabolism of absorbed nutrients
Storage organ for many minerals / certain vitamins
Energy storage to control blood glucose (glycogen can be approx 8% of liver fresh weight)
Bile production for effective fat digestion
Main site for detoxification (e.g., mycotoxins)
Synthesis of blood components
Hormone manufacture e.g., IGF (Insulin-Like Growth Factor)

10. “Metabolic Efficiency”
Gross Energy
Total energy of feed
Faecal Energy
Digestible Energy
(DE)
Energy "available" in blood
Urine Energy
Methane Energy
Metabolisable Energy
(ME)
Energy available at tissue level
Heat Energy
(during metabolism)
Net Energy
(NE)
Energy deposited in tissue / end product (meat, milk, eggs)

11. How do we maximise Metabolic Efficiency?
First focus on on-farm solutions
Quality of raw materials
Digestibility
Voluntary feed intake
Mycotoxins, etc
Correct and up to date formulations
Genetics
Feed processing
Management
Temperature / humidity
Quality of housing / floors
Stress factors (e.g. overcrowding)
Well-trained staff
Disease

12. How do we maximise Metabolic Efficiency?
What can we offer?

13. How do we maximise Metabolic Efficiency?

14. Acidpro
Unique Organic Acid blend researched and developed in South Africa for local conditions
Unique combination of organic acids improves digestibility and feed efficiency through several mechanisms
Improved pH conditions to allow for higher rate of protein digestion
Reduced protein in hindgut
Reduced risk of E. coli and associated endotoxin related disease

15. Acidpro Acidpro is more than just an ordinary organic acid blend
Also contains pre- and pro-biotics to ensure that beneficial micro-organisms are established and that they proliferate
Competitive exclusion of harmful micro-organisms

16. ClexVit ClexVit is a mycotoxin binder with a difference
3 pronged approach
1. Toxin binding
2. Toxin deactivation
3. Immune stimulation

17. ClexVit ClexVit is a mycotoxin binder with a difference
1. Toxin binding
Different types of clay
4 different yeast cell walls (exo- and endo-toxin binding)
Nanotechnology / advanced grid spacing
Large surface area

18. ClexVit ClexVit is a mycotoxin binder with a difference
2. Toxin deactivation
Enzyme forming yeasts
Liver stimulating additives

19. ClexVit ClexVit is a mycotoxin binder with a difference
3. Immune stimulation
Natural vitamin E
Organic Zinc and Selenium
Phosphorus improves carbohydrate and protein metabolism

20. ClexVit ClexVit is a mycotoxin binder with a difference
1 – 6 kg / ton depending on type of pig and severity of mycotoxin problem

21. What makes us unique?
Up to date science to research and develop on-farm solutions
Strategic symbiosis of products
Honest on-farm technical support
Your success is our success

22. Thank You